Amantadine for Levodopa-Induced Dyskinesias
نویسندگان
چکیده
منابع مشابه
Amantadine for levodopa-induced dyskinesias: a 1-year follow-up study.
BACKGROUND In a recent acute study, amantadine was found to have antidyskinetic effect against levodopa-induced motor complications in patients with Parkinson disease. The longevity of this effect was not addressed but is of interest in light of the controversy in the literature regarding the duration of amantadine's well-established antiparkinsonian action. OBJECTIVE To determine the duratio...
متن کاملLevodopa-induced dyskinesias in tyrosine hydroxylase deficiency.
The objective of this study was to characterize levodopa (l-dopa)-induced dyskinesias in patients with tyrosine hydroxylase deficiency. Clinical observation was carried out on 6 patients who were diagnosed with tyrosine hydroxylase deficiency and were treated with escalating doses of l-dopa. All 6 patients showed l-dopa-induced dyskinesias of variable intensity early in the course of treatment ...
متن کاملComment: Increased D3 binding-A substrate for levodopa-induced dyskinesias?
Levodopa remains the mainstay of treatment for Parkinson disease (PD), but its use is associated with dyskinesias (LID) in many patients. LID likely reflect dysregulated release of dopamine combined with altered postsynaptic mechanisms due to pulsatile dopamine receptor stimulation. Dopamine D receptors are increased in animal models of LID, and experimental LID is attenuated by suppression of ...
متن کاملFuture Scenarios for Levodopa-Induced Dyskinesias in Parkinson’s Disease
1 IBFM, National Research Council, Catanzaro, Italy 2 Laboratorio di Neurologia Clinica e Comportamentale, Fondazione Santa Lucia IRCCS, Rome, Italy 3 Morton and Gloria Shulman Movement Disorders Clinic and the Edmond J. Safra Program in Parkinson’s Disease, Division of Neurology, Toronto Western Hospital, UHN, University of Toronto, Toronto, ON, Canada 4 Dipartimento di Medicina Clinica e Sper...
متن کامل“Cueing” for Levodopa-Induced Dyskinesias in Parkinson’s Disease
We describe the case of an early-onset Parkinson's disease (PD) patient, suffering from a severe and unusual dyskinetic gait pattern, earlier described as "Silly walk." On presentation, the 58-year-old patient showed a painful, bizarre dyskinetic gait disorder, resulting in a significantly impairment of her social life. We developed an individual conservative training method for the patient, us...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 1999
ISSN: 0003-9942
DOI: 10.1001/archneur.56.11.1383